Long-term marijuana abuse has several negative impacts on the user, including:10 [6]

• Limiting the brain's capacity to store and retrieve information
• Damage to the brain's memory functions, as well as math and verbal skills
• Sexual dysfunction and reproductive problems, including irregular sperm and lowered sperm count in men and menstrual and ovulatory disruption in women
• Weakening of the immune system
• Increased risk of cancer and lung damage
• Increased blood pressure and risk of heart attack
• Loss of motivation and interest in everyday activities and future plans