Medical Marijuana and Epilepsy

CONTENT HIGHLIGHTS
  • Medical marijuana (also called medical cannabis) is whole plant marijuana or chemicals in the plant used for medical purposes.
  • Cannabinoids are substances in medical cannabis that act on cells in the body, including the brain. The two main cannabinoids used in medicine are tetrahydrocannabinol (THC) and cannabidiol (CBD).
  • The FDA recently approved the use of Epidiolex (a plant-based formulation of CBD) to treat seizures for people 2 years of age and older with Dravet syndrome and Lennox-Gastaut syndrome (LGS).
  • Medical cannabis, CBD, and THC all have possible side effects. The most common side effects of CBD included sleepiness, diarrhea, fatigue, and decreased appetite. CBD also interacts with some other seizure medicines.
  • Careful monitoring of CBD is needed.