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Consumption of cannabis during pregnancy results in cannabinoid placental crossing and accumulation in the fetal brain, and other organs, where it interferes with neurodevelopment and the endocannabinoid system. Use during the postnatal period can also lead to secretion in breast milk for extended periods (up to a week) after last use. From retrospective studies, we know prenatal cannabis ingestion has been associated with anemia in the mothers as well as low birth weights, greater risk of preterm and stillbirths, as well as increased need for neonatal intensive care unit admissions.

Pregnancy

CDC, the U.S. Food and Drug Administration (FDA), state and local health departments, and other clinical and public health partners are investigating a national outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI).

CDC, Vaping, states, Mapping

Vaping - Data Highlights Strong correlation between vaping nicotine and vaping marijuana:

  • 47.9% of current nicotine vapers are vaping marijuana
  • 72.2% of current marijuana vapers are vaping nicotine.
  • Most current nicotine vapers (72%) have NOT tried cigarettes.
  • Majority nicotine vapers (92%) have NOT smoked cigarettes in past 30 days.
monitoring the future, Vaping

Wild mass killings of this sort are a post-1960 phenomenon. So, applying the rules of logic, the availability of guns simply cannot be the significant variable.
It must be the single most successful rebranding in marketing history. Millions now associate a highly dangerous drug with miracle cures, health and wellbeing. Mr Stroup, understandably, has since denied the words, but the article is still sitting in the Emory library for anyone who wants to check.
Yet their product also ruins the lives of users and their families. And it kills. Often very terribly. Will this realization come too late to save us from a grave mistake?

stroup

A previous study last March in the Lancet also showed that cannabis use increases psychotic disorders such as schizophrenia.
Two preliminary studies presented this November out of Oklahoma and Virginia at the American Heart Association’s Scientific Sessions in Philadelphia tentatively connect cannabis use with doubled stroke risk and heart rhythm disorders.

People need to be educated that marijuana even 'medical' marijuana is not FDA approved and therefore is not a prescription.  Often contains mold, pesticides, fertilizers, unknown amounts of other chemicals and THC potency may be incorrect. 

In a recent cohort study of alcohol consumption in Canada, marijuana use was found to increase demand for alcohol. In other words, those who reported marijuana and alcohol use consumed significantly more alcohol than those who reported only alcohol use. The mechanism for this association is not entirely clear. However, these findings have important implications for treatment and prevention, particularly in the context of changes in marijuana legalization. In the USA, greater alcohol consumption can only mean increases in traffic fatalities and injuries, violent crime, and all the other negative population-wide outcomes and costs associated with alcohol and marijuana use. Interestingly, in Colorado, where marijuana has been legal for recreational use since 2014, all these negative indicators have been on the rise along with a conspicuous increase in alcohol consumption.

Canada, alcohol

Reason's Jacob Sullum and former New York Times reporter Alex Berenson debate eliminating laws that prohibit the use and sale of narcotics.

Berenson
File pot will kill you

I have never represented a heroin junkie or a meth head who didn’t start with marijuana.  Legalization of it is now all the rage in Democrat controlled states like Illinois, and it is a stupid mistake.  From Rod Dreher:
Berenson’s book is a game-changer. In his New Yorker piece, Malcolm Gladwell writes straightforwardly about the overwhelming scientific evidence that marijuana is a hell of a lot more problematic than many of us think. Excerpt:

Berenson begins his book with an account of a conversation he had with his wife, a psychiatrist who specializes in treating mentally ill criminals. They were discussing one of the many grim cases that cross her desk—“the usual horror story, somebody who’d cut up his grandmother or set fire to his apartment.” Then his wife said something like “Of course, he was high, been smoking pot his whole life.”
Of course? I said.
Yeah, they all smoke.
Well . . . other things too, right?
Sometimes. But they all smoke.

View the Dragnet video... same story for 50 years.  More research isn't going to change the outcome actually the outcomes with the stronger pot are getting worse and worse.  Did you know if research projects aren't going the way the funder desires they don't have to be published... How many studies have been scrapped because the results are negative, harmful, longlasting.... ?

Berenson, american catholic

The Hillsborough County Board of County Commissioners has determined that the prohibition on the sale, possession, and use of vapor‐generating electronic devices and vapor products should be extended to include young adults under the age of 21.

Vaping, tampa, Florida

VERMONT MEDICAL SOCIETY RESOLUTION- WHEREAS, non-prescribed CBD consumer products sold can contain up to 24 mg of THC, more than that of a typical cannabis joint, which contains up to 17 mg of THC, putting the consumer at risk for intoxication, unintended cannabis addiction relapse, and unintended mental health harm;

Vermont, CBD, medical association

While the total number of suicides is accurate (1,145), the number of toxicology results is likely higher than 888 – it’s just difficult/impossible for the state to obtain all the available toxicology results. For these reasons, an exact percentage of suicides with toxicology results can’t be calculated.

 

suicide, Colorado

Conclusion: These results underscore the importance of health advocate participation in developing cannabis legalization frameworks.

legalization, ncbi

The new SANDAG report, Marijuana Use Among San Diego Arrestees: Two Years of Data Post–Proposition 64 found that in 2018, 71% of adults and 53% of juveniles felt the potency of marijuana had increased since they started using, up from 63% and 39% respectively in 2017.

Vaping, Arrest, San Diego, california

The SAFE Banking Act (H.R. 1595/S. 1200) contains no public health guardrails to deal with the pot vaping crisis or incredibly potent flavored marijuana vapes that have been warned about by the Surgeon General. • The SAFE Banking Act would allow billions in investment into the same illegal marijuana companies that are creating marijuana vapes like those that are causing this crisis.

Vaping

video, Vaping
File The Doctor Is In: Answering Your Marijuana Questions

The Nation's Doctor, VADM Jerome M. Adams, M.D., answers top questions about marijuana. The U.S. Surgeon General addresses marijuana-related questions he often receives including those related to the chemical composition and potency of today’s marijuana, associated risks, and what parents and teachers can say to young people about marijuana.

surgeon General, video

Although this article is from 2010, the information is still relevant.  We now have more data to oppose legalization of marijuana for any reason.  

stimson, Heritage Foundation, talking points

In the past three years, teen suicide in Colorado rose from 12.9 to 20.4 deaths per 100,000 adolescents ages 15-19, according to the report. Overall, that rate put Colorado as the sixth worst state.
Nationally, the teen suicide rate is up 25 percent. Colorado's 2019 rate is nearly double that nationwide, 20.4 compared to 10.5

Colorado, suicide, Teens
Florida, Medical

The Florida medical marijuana market continues to expand at a rapid pace.
The two publicly held companies with the largest presence in the state are Trulieve followed by Curaleaf.
Extensive Florida operations have allowed Trulieve and Curaleaf to avoid the bear market that has engulfed multi-state operators MedMen, Acreage Holdings and Harvest Health.
Acreage Holdings' lack of ANY sales in Florida sends a strong signal that it is adrift.

Florida, Medical
Survey, SAMSHA

The Florida medical marijuana market continues to expand at a rapid pace.
The two publicly held companies with the largest presence in the state are Trulieve followed by Curaleaf.
Extensive Florida operations have allowed Trulieve and Curaleaf to avoid the bear market that has engulfed multi-state operators MedMen, Acreage Holdings and Harvest Health.
Acreage Hold

Medical, Florida

Link continues to update with information.  Latest from the Florida Department of Health on the Vape Lung Illness Crisis. The number of vape lung illnesses increased from 27 to 39. When will Governor DeSantis announce his plan to fight against this crisis? According to the CDC, most cases are linked to vaped marijuana (THC). What is the FL medical marijuana industry doing to protect patients? 

Vaping, Florida, Death

There they found an illegal cannabis product manufacturing operation apparently operated by Kushy Punch, a legal state-licensed company. Authorities seized a number of finished products, including gummies in Kushy Punch packaging and disposable vaporizers in Kushy Vape packaging.

Vaping

Talking Points:
• 77% of the cases of illness and at least 2 deaths have been connected to THC oils.
• At a time when we are investigating the causes of this rash of deaths and illnesses connected to marijuana oils and vapes, all marijuana legalization efforts and THC vaping oil sales should pause.
• This is not a black-market issue, it is the result of allowing Big Marijuana - an addictionfor-profit drug industry backed by Big Tobacco and companies like Juul - to mass produce these oils and vapes, along with candies, gummies, and other dangerously potent forms of the drug.
• Big Tobacco, E-Cigarette and Vaping Companies and the Marijuana industry share many of the same investors. The industries are connected by billions in investments.

Vaping, SAM

A new study finds that approximately one in three adolescents were exposed to marijuana promotions on social media or had a favorite marijuana brand.
 
Those who did had five times higher odds of past-year marijuana use.
 
Researchers recommend future studies might want to find ways to restrict marijuana marketing to young people.

Media, youth
Florida, youth, Survey

The lung damage in some people who have become ill after vaping nicotine or marijuana products resembles a chemical burn, doctors from the Mayo Clinic reported on Wednesday.

Vaping
The House of Representatives is about to consider a bill called The Safe Banking Act, which, like many titles of federal laws, is completely misleading. 
It should be called the “Let’s Pretend Marijuana Is Safe and Give Pot Pushers, Cartels, and Terrorist Organizations Access to Our Banking System” Act. 
Don’t hold your breath for a title change. Regardless of the title, the idea behind the act ignores reality and, if passed, will lead to disastrous results.
This bill is all about protecting people and businesses who openly commit federal crimes by selling marijuana, and rewarding them by giving them access to the most important banking system in the world to further give them the patina of legitimacy.
And at the same time the House is considering this bill, the data on the impact of the legalization experiment across the country is proving just what a dangerous and bad idea legalization has become.
The Rocky Mountain High Intensity Drug Trafficking Area report on the impact of legalization in Colorado is devastating for those pushing pot. The report found:
·          Traffic deaths where drivers tested positive for marijuana increased 109%
·         Traffic deaths involving drivers who tested positive for marijuana more than doubled between 2013 and 2018
·         The percentage of all Colorado traffic deaths that were marijuana related increased 15% in 2013 to 23% in 2018
·         Marijuana use in the past month for children ages 12 and up increased 58%, and is 78% higher than the national average
·         Adult marijuana use increased 94%, and is 96% higher than the national average
·         The yearly number of emergency room visits related to marijuana increased 54% after legalization
·         Marijuana-related hospitalizations increased 101% after legalization
·         Suicides where toxicology results were positive for marijuana increased from 14% in 2013 to 23% in 2017

The report also shows that the tax revenue from state-authorized marijuana sales, far from being a game-changer like pot pushers said it would be, amounted to around nine-tenths of 1% (000.9%) of Colorado’s fiscal year 2018 budget. Previous reports are just as bad. 

Pot Is a Schedule I Controlled Dangerous Substance for Good Reason

Passed in 1970, the Controlled Substances Act places marijuana in Schedule I, a category reserved for drugs that are medically unhelpful and dangerous. Schedule I drugs have a high potential for abuse, have no currently accepted medical use in treatment, and a lack of accepted safety for use even under medical supervision.

The fact that the act was controversial when it was adopted, and the debate over the proper treatment of cannabis has not quieted down since then, does not negate the fact that as of today, marijuana is on Schedule I.

As Heritage Foundation scholars have written elsewhere, Congress would be irresponsible to move marijuana out of Schedule I of the Controlled Substances Act without hearing from the nation’s finest scientific minds. 

States have passed so-called medical marijuana laws under the theory that pot has medicinal benefits that can’t be produced by other legal means. In making those claims, pot pushers want us to ignore the fact that today’s marijuana is one of the most genetically modified substances on the earth, has over 500 known carcinogens, has THC levels that dwarf the 1% or 2% levels from the 1970s (levels are now at 20-90% THC), and that there is zero quality, content, or dosage control in their products. 

They are also counting on you not knowing that there are already three FDA-approved THC drugs, and at least five more on the way.   

The dirty little secret they hide from you is that you don’t have to smoke marijuana, eat it in a brownie, or chew it in a marijuana-laced gummy bear to reap the medicinal benefits of THC. A doctor can write you a prescription for those drugs. They can’t write one for marijuana, because it is not a medicine

The three FDA-approved drugs are Marinol, Cesamet, and Syndros. Drugs like Syndros show great promise for countering today’s dangerous “medical marijuana” movement. The companies that sell those FDA-approved drugs do, and should have access to the federal banking system. But those who peddle pot, with sky-high genetically manipulated THC levels that have no medical benefit, shouldn’t.

stimson, blog, banking, Vaping, HR 1595, SB 1200, talking points

According to the department's statistics , there's been 27 reported cases of lung injury connected to vaping in Florida in 2019 and one death.

Vaping, Florida

What Do I Need to Know about Marijuana?   Podcasts   Answers all the myths with science and facts.  Is it safe to drive using marijuana?  If it is a medicine, how can it hurt me?  What does marijuana use do to my brain? ....

Podcasts, Brain, driving, Effects

But vaping has its own problems: Nicotine or THC, the high-inducing chemical in marijuana, is mixed with solvents that dissolve and deliver the drugs. The solvents, or oils, heat up during aerosolization to become vapor. But some oil droplets may be left over as the liquid cools back down, and inhaling those drops may cause breathing problems and lung inflammation.

  • Patients in this investigation have reported symptoms such as:
    • cough, shortness of breath, or chest pain
    • nausea, vomiting, or diarrhea
    • fatigue, fever, or abdominal pain
  • Some patients have reported that their symptoms developed over a few days, while others have reported that their symptoms developed over several weeks. A lung infection does not appear to be causing the symptoms.
Vaping
  • JUUL is a brand of e-cigarette that is shaped like a USB flash drive. Like other e-cigarettes, JUUL is a battery-powered device that heats a nicotine-containing liquid to produce an aerosol that is inhaled. 

  • All JUUL e-cigarettes have a high level of nicotine. According to the manufacturer, a single JUUL pod contains as much nicotine as a pack of 20 regular cigarettes.2

  • News outlets and social media sites report widespread use of JUUL by students in schools, including classrooms and bathrooms.

  • Although JUUL is currently the top-selling e-cigarette brand in the United States, other companies sell e-cigarettes that look like USB flash drives. Examples include the MarkTen Elite, a nicotine delivery device, and the PAX Era, a marijuana delivery device that looks like JUUL.

  • Additional information about USB-shaped e-cigarettes and actions that parents, educators, and health care  

  • CDC’s Infographic

Hacking the Juul- opening the pods to reload marijuana.  very potent. 

 

Healthy Kids Link- Spanish version

 

Another video

Vaping, Juul, Healthy Children

Vaping Pens... Honeycomb   - the "Pass Out Pen" 

  • The Ripper- The Ripper 2.0 is new, improved and the only Sub -ohm conceal (concealer) vaporizer for oils and wax ( as it is a 2 in 1 unit). High capacity, high powered vaporizer make it the most powerful pocket vape for oils and wax and also disguised as a light makes it ultra discrete. 
  • The Elf- "Small, compact, stylish and most importantly it is Auto-Draw button less design of this high quality aerospace feel ELF concealer. Available in 5 classy colors this small unit has effortless draws amounting in big rips and large vapor. Easy to use simply inhale. It is the only unit that is button less that can fit wide 510 thread cartridges with its magnetic adapter, and be a pull thru unit and still work with Ceramic heater cartridges that usually require more power to vape them.
  • '510' thread- five 10 thread-510 threaded is a term used to describe the threading that connects vape cartridges and batteries – there are 10 screw threads, and the cartridge is generally five millimeters in length (510). "510 Thread" has been used to describe all sorts of vape pen parts, whether they are threaded or not. It's a non technical term created by an original e-cig factory (Joyetech) to describe the battery to tank connection they were using. While it was considered proprietary at the time, this (and most other e-cig innovations) are passed around freely between manufacturers. Most pens today are all based on this 510 thread.
Vaping

The ABC7 I-Team has been given exclusive access to the largest set of test results and analysis on CBD products to date. Those tests reveal not only potential dangers, but also patently false claims plaguing the industry.

warning, labeling, CBD

Servicemembers are being told to avoid vaping after the Centers for Disease Control and Prevention said the habit may be linked to hundreds of cases of severe lung disease, and at least six deaths, in dozens of states.

Vaping, Veterans, Stars and Stripes

Teens who previously seemed impervious to smoking traditional cigarettes are now vaping at such a significant rate that the Surgeon General and FDA has declared youth use of e-cigarettes an epidemic.
 

  • 7 people have died from severe respiratory complications associated with vaping. At least 380 cases have been reported across the United States.
  • Early reports link marijuana vapes to 84 percent of the lung illnesses being reported in the wake of the vaping epidemic.
  • 84% of the cases of illness and at least 2 of the 7 deaths have been connected to THC oils.
Vaping, SAM

The FCC (Forensic Chemistry Center) is currently prioritizing samples that are most likely to enhance our understanding of this outbreak, i.e., vaping samples that are associated with cases of patient lung injury. If you have identified product samples with direct-association to case-illnesses in your state as part of your ongoing investigations, please reach out your local FDA District Emergency Response Coordinator or write to FDAVapingSampleInquiries@fda.hhs.gov for follow-up, collection, and shipment of samples to FCC through the utilization of FDA field staff.

Vaping, FDA, FCC

But  the  lives  of  vulnerable  people  may  be  put  at  risk when  science  is  distorted  for corporate  or  ideological  ends.  As  noted,  several  USstates  responded  to the  much-hypedoriginal study of cannabis and opioid overdosesby authorizing the use of medical cannabis to treat  heroin-addicted  individuals.  Advice  that  opioid  users  should use medical  cannabis toreplace  opioid  agonist  therapies  (e.g.,  methadone,  buprenorphine) poses significant  risk because abrupt cessation of these medications dramatically increases the risks of an overdose death if users return to opioid use 

Research, Medical, risks, opioid

America is getting pooped, thanks to trend-setting California. There is no getting around the fact that the Golden State is at the forefront of a defecation crisis which is already overflowing into neighboring states. The Left Coast has become the home of the homeless, the nation’s lost souls who apparently have settled for simply existing rather than really living. Sleeping out in the open spaces and pooping in public places are jarring signs that a segment of society has given up. The demoralizing, downward spiral is likely to accelerate unless Americans resolve to clean up their act.

Defecation, feces

In the study, published Monday in the journal Pediatrics, researchers surveyed almost 50,000 adolescents in Arizona. The researchers found that among teens who used any form of cannabis, 72 percent had experience with the more potent products.

Overall, the researchers found that 33 percent of the teens had tried some form of pot and 24 percent said they had used concentrated forms. The likelihood of a student using cannabis rose with age: 20 percent of the eighth graders said they’d used the drug, compared to 35 percent of the 10th graders and 46 percent of the 12th graders.

 

Similarly, 15 percent of the eighth graders, 25 percent of the 10th graders and 33 percent of 12th graders said they had used cannabis concentrates. Concentrate users had the highest rates of having tried other drugs.

 

consentrates, Teens, adolescent, Vaping

Colorado's violent crime rate continues to climb

Colorado

Just last year, the Parents Opposed to Pot lobby group tried to sound the alarm on the link between marijuana and mass shootings, compiling a list of mass killers it claims were heavy users of marijuana from a young age, from Aurora, Colo., shooter James Holmes and Tucson, Ariz., shooter Jared Loughner to Chattanooga, Tenn., shooter Mohammad Abdulazeez.
You can’t address the youth mental health crisis without considering the effect of rising teen marijuana use.
Among American teenagers, the drug’s “daily use has become as, or more, popular than daily cigarette smoking” according to the National Institute of Health’s 2017 Monitoring the Future study.
Another BMJ study estimated that “13 percent of cases of schizophrenia could be averted if all cannabis use were prevented.” That’s more than 400,000 Americans who could be saved from a fate worse than death.

guns, mental health, violence
guns, violence, mass killings

Toxicologist Peter Stout, CEO and president of the Houston Forensic Science Center, said the toxicology report showed low levels of anti-anxiety drugs and marijuana in Kelley's system.

guns, mass killings, violence

Conclusions and Relevance  This meta-analysis found a significant increase in the odds of past or current and subsequent marijuana use in adolescents and young adults who used e-cigarettes. These findings highlight the importance of addressing the rapid increases in e-cigarette use among youths as a means to help limit marijuana use in this population.

meta-analysis
powerpoint, legalization

Their observations and initial research show that marijuana use may affect patients’ responses to anesthesia on the operating table — and, depending on the patient’s history of using the drug, either help or hinder their symptoms afterward in the recovery room.
If pot users indeed need more anesthesia, are there increased risks for breathing problems during minor procedures? Are there higher costs with the use of more medication, if a second or third bottle of anesthesia must be routinely opened? And what does regular cannabis use mean for recovery post-surgery?

anesthesia, respiratory, Doctors

DISCUSSION AND CONCLUSIONS:
Medical and non-medical cannabis use both were both associated with increased risks of prescription opioid misuse. Medical cannabis use, however, was not associated with prescription opioid use disorder, and non-medical cannabis was. There appeared to be differential associations between cannabis use and prescription opioid use disorder by cannabis use purpose.

opioid

Conclusions: RWID and DUI are significantly associated with greater alcohol and marijuanause over time. This study highlights that teens may be at higher risk for problem substance use in the future even if they ride with someone who is impaired. Prevention and intervention efforts for adolescents need to address both driving under the influence and riding with an impaired driver to prevent downstream consequences.

drugged driving

Conclusions: Marijuana use varied in association with beliefs about its beneficial and harmful health properties. Clinical interventions that target specific marijuana-related health beliefs including unfounded claims of benefit may provide robust talking points for centering provider guidance and public health messaging.

youth, perception

FDA has determined that your “CBD Lotion,” “CBD Pain-Relief Patch,” “CBD Tincture,” and “CBD Disposable Vape Pen” products are unapproved new drugs sold in violation of sections 505(a) and 301(d) of the Federal Food, Drug, and Cosmetic Act (the FD&C Act), 21 U.S.C. 355(a) and 331(d). Furthermore, these products are misbranded drugs under section 502(f)(1) of the FD&C Act, 21 U.S.C. 352(f)(1). FDA has also determined that your “Bido CBD for Pets” products are unapproved new animal drugs that are unsafe under section 512(a) of the FD&C Act, 21 U.S.C. 360b(a), and adulterated under section 501(a)(5) of the FD&C Act, 21 U.S.C. 351(a)(5)

FDA, Curaleaf

Today, the U.S. Food and Drug Administration announced that it has issued a warning letter to Curaleaf Inc., of Wakefield, Massachusetts, for illegally selling unapproved products containing cannabidiol (CBD) online with unsubstantiated claims that the products treat cancer, Alzheimer’s disease, opioid withdrawal, pain and pet anxiety, among other conditions or diseases.

FDA, Curaleaf

Cannabis legalization has led to significant health consequences, particularly to patients in emergency departments and hospitals in Colorado. The most concerning include psychosis, suicide, and other substance abuse. Deleterious effects on the brain include decrements in complex decision-making, which may not be reversible with abstinence.

ED and urgent care (UC) visits with cannabis-associated International Classification of Diseases (ICD) codes or positive urine drug screens for teenagers and young adults have increased since legalization, and the majority require behavioral health evaluation. A subsequent retrospective review by Wang et al. from 2005–2015 identified 4202 such visits for patients 13 to <21 years old to a tertiary-care children’s hospital system. Behavioral health evaluation was obtained for 2813 (67%) and a psychiatric diagnosis was made for the majority (71%) of the visits. 

Colorado, ncbi, suicide
Texas, hemp

Cannabis is known to induce DNA damage by several mechanisms including damage to chromosomes at the time of cell division, dramatic reductions in histone formation which form the core of the nucleosomes around which DNA is twined and are crucially involved in signalling to the transcription and epigenetic machinery to regulate gene expression, alteration of DNA methylation and many other processes 2-6. And genotoxic stress of many types is known to trigger DNA checkpoints and interfere with the normal process of meiotic and mitotic cell division; and are also known to trigger ageing and cellular senescence pathways.
That it has been linked with all four areas, in the context of its many other known harms – respiratory, driving, impaired developmental trajectory, reduction in IQ, hippocampal shrinkage, brain disconnection and immunopathies - implies directly that the cannabis legalization debate itself is non-viable and profoundly and inherently misleading.

BMJ, genetics, Volkow

The AES believes that these compounds need to be under the full regulatory control of the FDA and that distribution should be limited to the well-developed legend drug process. While drug regulation is desired, in the interim, the following equally important steps should be taken to assure continuous and safe access to CBD products for patients who are currently benefiting from them.

american epiliepsy society, FDA, SAGE Journals
  • Thousands of businesses, as well as local governments earning tax money off of sales, are now literally invested in that lie.
  • “The mantra about how this is a harmless, natural, and non-addictive substance—it’s now known by everybody. And it’s a lie.”
  • As for new risks: In many stores, budtenders are providing medical advice with no licensing or training whatsoever. “I’m most scared of the advice to smoke marijuana during pregnancy for cramps,” said Humphreys, arguing that sellers were providing recommendations with no scientific backing, good or bad, at all.
  • “The reckless way that we are legalizing marijuana so far is mind-boggling from a public-health perspective,” Kevin Sabet, an Obama administration official and a founder of the nonprofit Smart Approaches to Marijuana, told me. 

 

Sabet

The study looked at 1991-2017 U.S. federal health data on more than 200,000 high school students. It found that the number who said they'd used pot at least once over the past month rose 10-fold -- from 0.6% in 1991 to 6.3% by 2017.

high school, Teens

An alarming finding shows that an estimated 14.8 million drivers report getting behind the wheel within one hour after using marijuana in the past 30 days. The impairing effects of marijuana are usually experienced within the first one to four hours after using the drug.1 And marijuana users who drive high are up to twice as likely to be involved in a crash.2

AAA, driving, driving drugged

In 2016 surveys, just 9% of medical schools had documented content on medical marijuana in the Association of American Medical Colleges Curriculum Inventory, and 85% of 258 surveyed residents and fellows reported having no education about medical marijuana in medical school or residency. Presented at a 2017 meeting, a single-site study of 51 resident physicians found that 76% did not know which category marijuana belonged to under the Controlled Substances Act (marijuana is currently categorized as a Schedule I drug, signifying a high potential for abuse and no accepted medical uses), and 38% believed that medical marijuana was a prescription drug approved by the US Food and Drug Administration. Other studies indicate that practicing physicians often have limited knowledge about marijuana’s health effects and want more training.”
That more than a third of the doctors surveyed in the small sample cited by Dr. Morris believed that marijuana is FDA-approved is shocking. I submitted a comment that was immediately published by JAMA. 
 

JAMA, Doctors

Then he started asking them, “do youJUUL?" and their answers changed.

 

“I wasn’t even asking the right questions, and I think a lot of clinicians still don’t ask the right questions,” Winickoff said. “Once I found out that kids were using, many of them thought that what they were using was not a big deal, that maybe they could stop any time they wanted. Some of them thought that vaping was just water vapor plus some flavor.”

Vaping, paraphernalia, high school

Alcohol is rapidly expelled from the system and is addictive only in large doses — at least to those … whose genetic make-up has been influenced by the millennia of winemaking.” Furthermore, “the effects of cannabis remain for days, and it is both more addictive and more radical, leading not just to temporary alterations of the mind but to permanent or semi-permanent transformations of personality, and in particular to a widely observed loss of moral sense.” 

It also has many physical effects, such as greater carcinogenic harm than smoking cigarettes. Unlike consuming a foodstuff in moderation, the consumption of cannabis immediately affects the functioning of the brain, an effect compounded over time, especially for adolescents. In fact, marijuana usage can permanently alter the brain, leading to a great risk of psychosis, psychological problems, and lower I.Q. scores. Further, one of the most frightening discoveries shows that consuming marijuana alters DNA, creating harmful mutations that will be passed down to children and future generations. 

alcohol

"If it's not USDA Organic certified, and it's not full panel lab tested, you have no way of knowing what you're getting," said Cranford, who's been producing CBD long before it was en vogue.

"Overseas they use hemp to do cover crops. They use it to purposely suck out the pesticides and heavy metals on soil there so they can plant food crops next," Cranford said. "These crops are being imported into the US and people are making CBD out of it. The really scary part is when you have these contaminants in your plant material, and you make this oil, you're concentrating it."

After thousands of tests, 70 percent of products were found "highly contaminated" with heavy metals like lead and arsenic, herbicides like glyphosate (the active ingredient in RoundUp) and a host of other contaminants including pesticides, BPA and toxic mold.

Virginia Commonwealth University, the Journal of the American Medical Association, and other medical journals have published studies that reflect similar outcomes to the hundreds of tests done by Ellipse Analytics, citing contamination, false labeling and false claims.

contaminated

Contrary to what you've been told over and over, it is not a preposterous assertion that marijuana is a gateway drug to cocaine, heroin, meth and such. Not everybody who smokes marijuana graduates to harder narcotics, true. But most of those who do go on to the harder stuff start off with weed.
Video on Snake Oil

opinion, snake oil, Neese
Florida

A Paulding County student collapsed and nearly died after taking a hit off a vape pen. The dramatic scene unfolded in front of a class when the South Paulding High School student collapsed and stopped breathing.
 
*** This is exactly why we need to raise the age for purchasing these products to 21... give our youth a chance.

Vaping, Georgia, adolescent
resource

The study found that a number of brain disorders and behaviors predicted accelerated aging, especially schizophrenia, which showed an average of 4 years of premature aging, cannabis abuse (2.8 years of accelerated aging), bipolar disorder (1.6 years accelerated aging), ADHD (1.4 years accelerated aging) and alcohol abuse (0.6 years accelerated aging). Interestingly, the researchers did not observe accelerated aging in depression and aging, which they hypothesize may be due to different types of brain patterns for these disorders.

study, Brain, aging, science daily

Adolescent Marijuana Use increases in Florida

adolescence, Florida

In 2011, just over 5,500 reports were logged by the San Francisco Department of Public Works; in 2018, the number increased to more than 28,000.

San Francisco, california, feces

She quit marijuana completely for three months and was symptom-free. Then she tried CBD, hoping there was some form of cannabis she could enjoy. One day she took 200 milligrams of CBD in capsules. That night, she ended up in the ER.   cannabinoid hyperemesis syndrome, or CHS.

Hyperemesis Syndrome, business insider
Fried

The study authors consider high-potency cannabis to be products with more than 10 percent tetrahydrocannabinol or THC, the compound responsible for the drug's psychoactive effects. The fact that consuming high-THC cannabis products has a greater risk is concerning, Lisdahl says, because these products are more common in the market now.

Now a new study published Tuesday in the The Lancet Psychiatry shows that consuming pot on a daily basis and especially using high-potency cannabis increases the odds of having a psychotic episode later.

study, Potency, Lancet, Psychosis

In conclusion, our findings confirm previous evidence of the harmful effect on mental health of daily use of cannabis, especially of high-potency types. Importantly, they indicate for the first time how cannabis use affects the incidence of psychotic disorder. Therefore, it is of public health importance to acknowledge alongside the potential medicinal properties of some cannabis constituents the potential adverse effects that are associated with daily cannabis use, especially of high-potency varieties.

Research, study, Lancet, Potency, Psychosis

It is the latest in a long line of evidence that marijuana is not an innocent relaxation drug. “Smoking high-potency cannabis, used daily, has been linked to diagnosis of conditions like schizophrenia, paranoia and other psychosis disorders, new findings say. About 50 percent of new cases of psychosis disorders diagnosed in Amsterdam were linked to use of high-potency cannabis, according to a study published Tuesday in The Lancet.

mental health
  • cannabis is safe and helpful for PTSD are limited by either anecdotal or poor quality evidence, are offset by studies reporting opposite conclusions, and the well-demonstrated potential harms of cannabis addiction and risk for psychosis are not adequately weighed in the decision to recommend medical cannabis treatment of chronic PTSD
  • There is a consensus that multiple social harms associated with cannabis legalization are not being adequately addressed. These include concerns about youth exposure under age 25 (a time of highly active brain development) and youth-marketing of edible cannabis products (eg, gummy bears and other confections) and cannabis concentrates that are easily obtained and “vaped”; unintentional in utero exposure prior to a woman’s knowledge of pregnancy; increased rates of intentional cannabis use during pregnancy; driving impairment and the absence of appropriate technological and legal systems to detect and deter this (equivalent to the breathalyzer for alcohol impairment); and cannabis use in sensitive occupations such as public transportation, public protection, and health services. While the voting public and industry is moving cannabis expansion forward, state proceedings have not yet involved public health, neurodevelopmental experts, and experts in addiction psychiatry and medicine equally with industry and economy experts. This is anything but reassuring for all who keep in mind that the United States is by far the greatest demand population for psychoactive substances, worldwide.4
voting, Legislation

Significant effects of prenatal cannabis exposure have been found on children's sleep, cognitive functions (memory and scholastic skills), as well as on executive (frontal lobe) functions (reasoning, attention, impulsivity, and motivation), and affective (depression) and anxiety symptoms throughout the stages of development. Following the presentation of two case vignettes, we integrate the published information on outcomes of maternal use of cannabis during pregnancy on the developing fetus and the "soft" neurological deficits and neuro-behavioral disturbances manifested by them from early childhood and evolving to peaks in adolescence. Taken together, these data serve to define what we call a heretofore unspecified "fetal cannabis spectrum disorder".

Pregnancy, PubMed
  • The reality is that the medical marijuana argument is meant mostly to protect recreational users from legal problems.
  • One in every 15 alcohol drinkers  drink every day while one in every five marijuana users do so daily.
  • America is the Western country that uses the most marijuana and has the worst problem with opioids.
Berenson
smoking, Environment

CONCLUSIONS:
Early cannabis use is associated with psychosis-related outcomes in young adults. The use of sibling pairs reduces the likelihood that unmeasured confounding explains these findings. This study provides further support for the hypothesis that early cannabis use is a risk-modifying factor for psychosis-related outcomes in young adults.

Truth, hallucinations, cannabis-induced psychosis, Psychosis

Is the solution to the opioid epidemic as simple as the legalization of medical cannabis? Commenting on the Bachhuber et al. analysis (1), Finney et al. (4) cautioned that an ecological fallacy may be present—individuals using medical marijuana could have elevated overdose mortality rates even though there is a state-level reduction. They contended that a prospective study of individual pain patients was necessary to assess relationships between cannabis use, use of opioid medications, and other substance use (4).
 

olfson, opioid

The authors discovered several interesting things. First, all elements of both alcohol and cannabis use increase annually across the various levels of frequency of use, with the exception of daily alcohol use. Second, the effects of cannabis are considerably greater than those of alcohol. Third, there appear to be both concurrent and lagged effects of cannabis use on several cognitive domains. Thus, use of cannabis has persistent effects that are also exacerbated by continued use.

psychiatry, cognition

Two cases of sudden death are reported in patients whose self-determined seizure management primarily relied on artisanal cannabis therapies. Risks of morbidity, mortality and SUDEP in SDTC users need to be further studied. Providers should be aware of the absence of morbidity and mortality data for SDTC in patients with epilepsy may only be due to a failure of reporting.

epilepsy, science direct, Death

Experts define addiction as continued marijuana use despite negative consequences in a person's life, such as issues relating to their family, job, or relationships.
People who use marijuana regularly and then stop abruptly can experience some withdrawal symptoms.

withdrawal, addiction, medicine news today

I was surprised, to say the least. I tended to be a libertarian on drugs. Years before, I’d covered the pharmaceutical industry for The New York Times. I was aware of the claims about marijuana as medicine, and I’d watched the slow spread of legalized cannabis without much interest.
Jackie would have been within her rights to say, I know what I’m talking about, unlike you. Instead she offered something neutral like, I think that’s what the big studies say. You should read them.....

book, Berenson

Given today's concerns about maintaining a healthy body eating organic foods, low carb diets, ... reading all the labels to verify safety and good health, it is ironic the same standards are not demanded by those that consume marijuana.  Dog food is safer than marijuana!

For example, smoking pot is widely supposed to diminish the nausea associated with chemotherapy. But, the panel pointed out, “there are no good-quality randomized trials investigating this option.” We have evidence for marijuana as a treatment for pain, but “very little is known about the efficacy, dose, routes of administration, or side effects of commonly used and commercially available cannabis products in the United States.” The caveats continue. Is it good for epilepsy? “Insufficient evidence.” Tourette’s syndrome? Limited evidence. A.L.S., Huntington’s, and Parkinson’s? Insufficient evidence. Irritable-bowel syndrome? Insufficient evidence. Dementia and glaucoma? Probably not. Anxiety? Maybe. Depression? Probably not.

“dose-response relationship”... non-existent!

New Yorker

In 2017 Colorado had a record number of opioid overdose deaths from any opioid, including heroin and Colorado has had a medical marijuana program since 2001.
There are several reasons as to why any reported benefit will be outstripped by lack of benefit and increased risk of harm, and why cannabis is contributing to ongoing opioid use, and subsequently, the opioid epidemic.

  1. There is evidence in animal models showing adolescent rats exposed to THC will develop enhanced heroin self administration as adults which may be due to activation of mesolimbic transmission of dopamine by a common mu opioid receptor mechanism.,
  2. More than 90% of heroin users report a prior history of marijuana use compared to a prior history of painkiller use (47%).13
  3. Prospective twin studies demonstrated that early cannabis use was associated with an increased risk of other drug abuse. This particular study was conducted when the THC content was much lower than todays products which can reach 95% THC.
  4. Currently there is no widely available or accepted medical literature showing any benefit for pain with dispensary cannabis in common pain conditions. 

There is currently a large and growing body of evidence showing that cannabis use increases, rather than decreases non-medical prescription opioid use and opioid use disorder, based on followup of more than 33,000 people. Concurrent use of cannabis and opioids by patients with chronic pain appears to indicate a higher risk of opioid misuse. Closer monitoring for opioid-related aberrant behaviors is indicated in this group of patients and it suggests that cannabis use is a predictor of aberrant drug behaviors in patients receiving chronic opioid therapy.
There is sufficient and expanding evidence demonstrating that medical marijuana use will not curb the opioid epidemic. There is further evidence that marijuana is a companion drug rather than substitution drug and that marijuana use may be contributing to the opioid epidemic rather than improving it.

opioid, Finn, ncbi
abuse

Not good news!
Only 5 Republican Governors got passing grades from NORML and the 2nd highest grade (C) of this group was Ron DeSantis. :-( The only Republican Governor who got a higher grade (B+) was the Gov. of Vermont who signed a bill that legalized recreational pot! Most Republican governors got Ds and Fs.

norml, governor

Large-scale, longitudinal studies of humans whose mothers smoked marijuana once or more per week and experimental work on rodents exposed to cannabinoids in utero have yielded remarkably consistent intellectual and behavioral correlates of fetal exposure to this drug. Some exposed individuals exhibit deficits in memory, cognition, and measures of sociability. These aberrations appear during infancy and persist through adulthood and are tied to changes in the expression of multiple gene families, as well as more global measures of brain responsiveness and plasticity. Researchers currently consider these perturbations to be mediated by changes to the endocannabinoid system caused by the active compounds in cannabis. 

Pregnancy

The seven most frequently occurring drugs found in decedents were ethyl alcohol (5,258), benzodiazepines (5,064, including 1,889 alprazolam occurrences), cocaine (3,129), cannabinoids (2,367), fentanyl (2,088), morphine (1,992), and fentanyl analogs (1,685). Since heroin is rapidly metabolized to morphine, this may lead to a substantial over-reporting of morphine-related deaths as well as significant under-reporting of heroin-related deaths.
Cannabinoids 7 (cause of death)   2,360 (present)  2,367 (total)
 
 

fatal, Florida, Death

As state lawmakers continue hashing out a marijuana legalization bill, the list of towns in New Jersey saying no to legal weed just keeps growing.
There are now nearly 40 municipalities across the state that have either banned marijuana businesses or officially voiced opposition to legal weed.

New Jersey, Ban

The advisory mentions the following risks:
1. Marijuana is addictive. Approximately one in eleven individuals who use marijuana will become addicted. The risk is greater in youth. One in six teenagers who use marijuana will become addicted, and the risk for developing a marijuana substance use disorder further increases for those who use marijuana frequently.....

TN, Public Health, Advisory

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