Potency

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The Role of the Physician in “Medical” Marijuana asam, Potency, cannabis

 All cannabis‐based and cannabinoid medications should be subjected to the  rigorous scrutiny of the Federal Food and Drug Administration (FDA) regulatory process.  This process provides important protections for patients, making medications available  only when they: 1) are standardized by identity, purity, potency and quality; 2) are accompanied by adequate directions for use in the approved medical indication; and 3)  have risk/benefit profiles that have been defined in well‐controlled clinical trials. 

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Risks of increasingly potent Cannabis: The joint effects of potency and frequency Potency

Cannabis potency has risen significantly over the past several decades, with available evidence pointing to an increased risk of Cannabis use disorder, psychosis, acute cognitive impairment, and structural brain changes with use of high-potency Cannabis. Clinicians should consider asking patients who use marijuana about potency to better assess risk of psychiatric adverse effects.

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The Clinical Conundrum of Medical Marijuana Potency, Studies, driving, Finn, MD, 2017 Legislation

Detailed Information
. Patients freely share their “medicine” with family and friends, and parents are self-diagnosing, and subsequently dosing their children with high-concentration marijuana products for conditions that may simply not exist (attention-deficit/hyperactivity disorder, anxiety, etc.); or allow their medical cards to expire and continue to grow their own.
The use of marijuana for medical conditions, including pain, needs robust studies, and subsequent products need more regulation and consistency for public consumption. Colorado is an example of the societal effect across a wide spectrum of arenas that comes with rampant cannabis use, particularly in youth use and impaired driving fatalities. The problems Colorado is seeing completely transcend “responsible use” or “marijuana as medicine.” 

 

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Not Your Mom’s Pot: How Increased Potency Has Changed Marijuana Consumption Potency

Marijuana is typically four-times stronger than it was a couple decades ago. On top of the boosted potency, since legalization, growers have been able to refine their skills to grow strains for unique and specific ailments. Not to mention the exploding market of concentrates and dab culture.

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Marijuana or Alcohol: Which is more harmful? alcohol, harm, Potency, Pharmacokinetics, powerpoint

PowerPoint Presentation comparing Marijuana & Alcohol,

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Why Is It So Hard To Test Whether Drivers Are Stoned? Potency, impaired, drugged driving, DUI

The simple fact that THC is fat soluble. That makes it absorbed in a very different way and much more difficult to relate behavior to, say, [blood] levels of THC or develop a breathalyzer."  The height of your intoxication isn't at the moment when blood THC levels peak, and the high doesn't rise and fall uniformly based on how much THC leaves and enters your bodily fluids, says Marilyn Huestis, who headed the chemistry and drug metabolism section at the National Institute on Drug Abuse.

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Potent Pot: Marijuana Is Stronger Now Than It Was 20 Years Ago CBD, Psychosis, Potency

Pot is becoming more potent, a new study suggests.
In the study, the researchers looked at more than 38,600 samples of illegal marijuana seized by the U.S. Drug Enforcement Administration over 20 years. They found that the level of THC, or tetrahydrocannabinol— marijuana's main psychoactive ingredient — in the marijuana samples rose from about 4 percent in 1995 to about 12 percent in 2014.
Conversely, the level of CBD, or cannabidiol — an ingredient sometimes touted for its potential health benefits — fell from about 0.28 percent in 2001 to less than 0.15 percent in 2014.
But smoking marijuana with high doses of THC may involve a higher risk of negative health effects, such as psychosis orpanic attacks, he said.
"Great article- clearly based on the previous posted comments  marijuana severely impairs a person's ability to understand and process information. Their anecdotal evidence continues to validate scientific statistics. " -No2Pot

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Study: High-potency marijuana linked with neural damage Studies, Brain, Potency

"We found that frequent use of high-potency cannabis significantly affects the structure of white matter fibres in the brain, whether you have psychosis or not," 
The main psychoactive ingredient in weed, tetrahydrocannabinol (THC), is much more concentrated in modern skunk strains as compared to traditional pot and hash -- up 14 percent as compared to 4 percent.

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Legalization of Marijuana- Impact Report Colorado, Potency, youth usage, vehicle, social costs, Business

See report for details, graphs, data.

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Where There’s Smoke … youth, Colorado, college, Potency, legalization, alcohol

Marijuana use by kids between the ages of 12 and 17 is 58 percent higher in Colorado than the national average, according to the RHMIDTA. The rate of use among college-age adults is 54 percent above the national average. Drug-related suspensions from Colorado schools jumped 34 percent from the 2005-2009 period to the 2010-2014 period, while alcohol-related suspensions stayed flat.
 "Everything they said would happen has not," says Gorman. "They said alcohol use would go down. Alcohol use went up. They said it would eliminate the (marijuana) black market. We are the black market. The trends show that legalization is not working."
 

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Many Medical Marijuana Edibles May Have Inaccurate Labels edibles, Potency

The majority of the products we tested were inaccurately labeled," said study author Ryan Vandrey, of The Johns Hopkins University School of Medicine in Baltimore.

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THC extracts concentrate problems clearing the haze, Potency, THC levels

The proliferation of foods infused or coated with THC has become a growing concern, even among some marijuana advocates. Several high-profile marijuana crimes and deaths involve consumption of edible THC products.
“When THC is available in food, it’s even harder for people to see it as a drug,” Lewis said. “But it is a drug. It is a depressant, a hallucinogen and an addictive substance that changes chemistry in the brain. Research shows all of the above.”

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Marijana is not Harmless chemicals, vehicle, Potency

Marijuana contains more than 400 chemicals. The primary psychoactive chemical is delta-9- tetrahydrocannabinol (THC) and is the component of marijuana principally responsible for the “high” experienced by pot smokers. Along with the high, users exhibit slower reflexes and decreased coordination. Marijuana also impairs judgment. Slower reaction times, impaired judgment, and problems responding to signals and sounds equal dangerous drivers. No wonder those who drive within three hours of smoking marijuana are twice as likely to be involved in a major car crash.

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CAN YOU SMELL A SKUNK IN THE STINKY CLAIMS FOR MARIJUANA? THC, CBD, Potency 14
Marijuana three times stronger than in the 1980s, lab tests report. Colorado-0, Potency, THC 15
Colorado Marijuana Study Finds Legal Weed Contains Potent THC Levels Potency, Colorado, GMO

In old-school dope, levels of THC — the psychoactive chemical that makes people high — were typically well below 10 percent. But in Colorado's legal bud, the average THC level is 18.7 percent, and some retail pot contains 30 percent THC or more, according to research released Monday.
"This shows that marijuana is a GMO product just like other products sold by big business. And just like other industries, now you have a big marijuana industry determined to hide these findings from the public. Where is their outcry? Where are the promises to change the way they do business?" 

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Medical Marijuana: The State of the Science Potency, Studies, lungs, cigarettes, Pregnancy

State of the Science   190 resources
Several problems are associated with marijuana use during pregnancy, because prenatal exposure influences brain development and can result in permanent cognitive impairment. [35] Cognitive deficits resulting from prenatal exposure include inattention; impulsivity; and impairment in learning, memory, and certain aspects of executive functioning. [36] In addition, prenatal exposure to cannabis has been associated with reduction of fetal growth. [37]
For many years, the myth of smoked cannabis being "healthier" or "no worse" than smoked tobacco was perpetuated by pro­marijuana groups. Both smoked cannabis and tobacco contain approximately 4000 chemicals and that these chemicals are essentially identical in both plants.In another recent review, [23] the authors concluded that "smoking of cannabis is not medically recommended due to the potential respiratory tract, dangers of noxious compounds such as polycyclic aromatic hydrocarbons, tar and carbon monoxide."
 
 

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Ed Wood- FL per se law Wood, Potency, 2017 Legislation

Based upon the foregoing evidence, this author has a clear preference for zero tolerance laws to deal with the increasing scourge of DUID.  The increasingly accepted Libertarian view is that such laws criminalize personal choices that cause no harm to citizens other than the drug consumer.  Laws requiring probable cause be first established before requiring a blood sample theoretically alleviate this concern, but are unconvincing to opponents of zero-tolerance laws.  Adoption of New Zealand’s approach is suggested as a means of gaining acceptance of zero tolerance laws without unduly harming Libertarian sensitivities.

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Futile Search Wood, Potency, 2017 Legislation

The fact is that there is no level of THC in blood above which everyone is impaired, and below which no one is impaired.  This is not because we need more studies; it’s because of human biology. Consider the following three factors.

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Legalise cannabis – and children will pay the price youth, mafia, Potency, Colorado, edibles

The emerging marijuana industry in Colorado is trying to appeal to teenagers by offering cannabis-infused soda, chocolate taffy and jujubes.

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Charlotte’s Web law far different from Amendment 2 Charlotte's Web, Potency 21
Editorial: Not your father’s marijuana Potency, recreational

The paper points out that the potency of marijuana has increased fourfold since the 1980s and can hardly be compared to the less harmful drug millions of pot smokers used decades ago.
And opponents point to Colorado and Washington, where the passage of medical marijuana in 2000 and 1998, respectively, were followed by the passage of recreational marijuana laws in 2012.

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Is Pot Getting More Potent? Potency, impaired 23
A Look Inside Colorado’s Pot Industry Colorado-0, edibles, Potency

We welcomed in a new industry that knowingly promotes an addictive and harmful substance SO THAT PEOPLE COULD MAKE MONEY. The business of business is to make money and when there is money to be made people will signup no matter how messed up the means are. 
For these businesses to continue making the huge money they are making they will need to do two things: 1) engage new users, 2) convert current users to more frequent users.
Our weed in Colorado is so strong (20-30 percent THC in its smoked form) that we have a strain called “green crack.”
Our concentrates, which are advertised aggressively, are 80-90 percent THC, and are often smoked on a super-heated needle and puts the smoker on their back with one hit.  Our edibles come in gummies, fruit sodas, suckers, candy and yummy looking baked goods that are so potent that a single pot brownie in Colorado comes with a warning that it has to be cut into fourths before consuming.

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Has the potency of pot changed since President Obama was in high school? Potency, kennedy, obama, GMO

Marijuana today is "genetically modified," with THC levels that "far surpass the marijuana" of the 1970s.    YES

The number of samples confiscated with a THC concentration greater than 9 percent has increased significantly, from 3.2 percent in 1993 to 21.5 percent of the 1,635 marijuana samples collected in 2007.

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Potency of Marijuana Potency, Psychoactive 26
Everything you needed to know about CBD CBD, SAM, Potency, THC

There is absolutely no reliable scientific evidence that THC is necessary to synergize the effects of CBD. Instead, there is evidence from preclinical research that THC may be pro-convulsant in sensitive brains; other research indicates that chronic use of THC can impair IQ in adolescents. Physicians are beginning to report instances of THC toxicity in children taking “high CBD” preparations, e.g., high anxiety, increased seizures, insomnia, etc. Until more is known, the most conservative course of action would be to remove THC entirely from a CBD product.

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Marijuana potency surpasses 10 percent, U.S. says Potency 28
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