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The Role of the Physician in “Medical” Marijuana 05/15/2017	All cannabis‐based and cannabinoid medications should be subjected to the rigorous scrutiny of the Federal Food and Drug Administration (FDA) regulatory process. This process provides important protections for patients, making medications available only when they: 1) are standardized by identity, purity, potency and quality; 2) are accompanied by adequate directions for use in the approved medical indication; and 3) have risk/benefit profiles that have been defined in well‐controlled clinical trials. asam, Potency, cannabis
E-Cigarettes: A Review of New Trends in Cannabis Use 10/08/2015	Pharmacokinetic and pharmacodynamic investigations are also required. Finally, the health consequences of passive vaping should be also considered. In conclusion, the new social phenomenon of vaping may slide from nicotine towards other psychoactive drugs (e.g., THC); it therefore deserves the urgent scientific investigation and strict risk assessments which are especially important when young people are concerned. In particular, the presence of toxic substances in the cannabis aerosols generated by e-cigs—from multiple models, brands, BHO and e-liquid manufacturers—need to be investigated. A synthesis of the practical recipes and experiments reported on the Internet (in addition to our own experiments) shows that the simple, direct use of purified cannabis extracts in e-cigs is not easy because cannabinoids are poorly soluble in e-liquids. Indeed, used pure or in mixture with glycerol, the propylene glycol (PG, or propane-1,2-diol) that is commonly used in e-liquids has both hygroscopic and hydrophilic properties. Consequently, it is not miscible with mineral and vegetable oils and fats. In contrast, cannabinoid concentrates are very lipid soluble, but water insoluble. Furthermore, PG, glycerol, terpenoids, plant fats and waxes, cannabinoid concentrates and THC are very viscous substances. Accordingly, the manufacture of a homogeneous solution using these viscous liquids is a tedious task. Cannabinoid concentrates resemble more a thick, sticky, gummy resin than a liquid. We can infer from these facts that they do not mix readily with glycols, and even less so with glycerol. The addition of terpenoids (e.g., limonene) or lecithin has been advocated to help make cannabis oils miscible... cannabis, Vaping, electronic cigarette, adolescence, youth, e-cig
Medical Marijuana: The State of the Science 02/06/2015	Medical cannabinoids are here to stay, but intellectual honesty is imperative if we are moving toward exploiting their potential benefits. Owing to rising THC concentrations of products, "medical" marijuana is rarely good medicine. This review has identified the dangers associated with wholeplant marijuana, whether used for recreational or for supposedly medical purposes. Studies, Research, medscape, mental health, Side-Effects, heart, lungs, body, Brain, youth, cannabis, Resource Paper
Cannabis Has Medical Value; Medical Marijuana is a Fraud 01/05/2015	But having medical value” isn’t the same thing as “being a medicine.” A medicine is a material of known chemical composition and dosage that has been shown in clinical trials to be safe and effective in the management of some condition in some patient population. By that standard, natural cannabis can’t be a medicine, simply because natural cannabis varies so widely in its chemical content: not only from one strain to another, but from one plant to another and even from one bud to another from the same plant. “Blow some weed” is not a prescription. That’s the reason that “rescheduling” cannabis to recognize its medical value is a non-starter legally; rescheduling needs to follow clinical research, and would apply only to specific products, not to the plant generically. cannabis, Fraud, Rx Drugs