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Title | |
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How Cannabis Causes Paranoia: Using the Intravenous Administration of Δ9-Tetrahydrocannabinol (THC) to Identify Key Cognitive Mechanisms Leading to Paranoia [1] 07/10/2015 |
The principal psychoactive constituent of cannabis is Δ9-tetrahydrocannabinol (THC). THC administered intravenously is characterized by the appearance of psychopharmocological effects within 5 minutes, which continue for at least 90 minutes, providing an excellent experimental window.[12] In within-subjects tests with nonclinical volunteers, D'Souza, in particular, has shown that intravenous administration of THC causes schizophrenia-like symptoms, perceptual disturbances, anxiety, and impaired working memory (eg, Morrison et al[13] and D'Souza et al[14,15]). Similar but more pronounced results were found in patients with schizophrenia.[15] Schizophrenia [2], paranoia [3], Studies [4], Research [5] |
Links
[1] http://rethinkpot.org/how-cannabis-causes-paranoia-using-intravenous-administration-%CE%B49-tetrahydrocannabinol-thc-identify
[2] http://rethinkpot.org/tags/schizophrenia
[3] http://rethinkpot.org/tags/paranoia
[4] http://rethinkpot.org/tags/study
[5] http://rethinkpot.org/tags/research