Articles

10/11/2015

At the moment, there simply isn’t enough evidence to prove that cannabinoids – whether natural or synthetic – works to treat cancer in patients, although research is ongoing. And there’s certainly no evidence that ‘street’ cannabis can treat cancer.

10/09/2015

Levy says. “We are simply not prepared for the fallout of marijuana legalization.”
Each hit of THC rewires the function of this critical cognitive system: Early evidence in mice has shown that repeated exposure to THC causes these receptors to disappear altogether, blunting the natural response to positive behaviors and requiring higher doses to achieve the same effect. Marijuana exploits essential pathways we’ve evolved to retrieve a memory, to delicately regulate our metabolism, and to derive happiness from everyday life.

10/07/2015

“I think we’re going to be seeing a lot of similar lawsuits in other states,” Malsbury said, pointing out that the nation’s largest marijuana producer, California, has no pot regulations at all. Medical marijuana is grown and sold in California but recreational sales remain against state law.

09/30/2015

There has not been an overall change in the amount of pain that Americans report,1,2 yet the amount of prescription painkillers dispensed in the U.S. quadrupled since 1999.3 Changes in how providers prescribe painkillers has helped fuel this epidemic. There is wide variation in painkiller prescribing between states which can't be explained by differences in health issues from state to state.

Deaths from prescription painkillers have also quadrupled since 1999, killing more than 16,000 people in the U.S. in 2013.4Nearly two million Americans, aged 12 or older, either abused or were dependent on opioids in 2013.5

09/30/2015

The National Survey on Drug Use and Health (NSDUH) is the primary source of information on the prevalence, patterns, and consequences of alcohol, tobacco, and illegal drug use and abuse and mental disorders in the U.S. civilian, non-institutionalized population, age 12 and older. The survey generates estimates at the National, state, and substate levels.

09/30/2015

“Every state must take steps to reduce drug-impaired driving, regardless of the legal status of marijuana,” said Jonathan Adkins, Executive Director of GHSA. “This is the first report to provide states and other stakeholders with the information they need. And we encourage NHTSA to issue guidance on best practices to prevent marijuana-impaired driving. We look to the federal government to take a leadership role in this issue similar to that of drunk driving and seat belt use.”

09/24/2015

Olympia, WA – Newly released data from the Washington Traffic Safety Commission (WTSC) shows that marijuana is increasing as a factor in deadly crashes. The number of drivers involved in deadly crashes who tested positive for marijuana increased 48 percent from 2013 to 2014. 
“This study is a step towards answering the myriad of questions we have about the impact of legalized marijuana on driving.

09/21/2015

• Prenatal exposure to marijuana has been shown to be predictive of psychotic symptoms in young adulthood.
• Monitoring the Future survey reported a five-year decline in the perceived harm of regularly smoking marijuana, from 52.4% of high school seniors to 36.1%
• Marijuana is the most widely used illegal drug in the United States and it is estimated that it is used by 61% of all persons suffering from a substance use disorder related to drugs other than alcohol.
• The risk of developing addiction associated with cannabis use has been reported to increase to about 17% among those who start using marijuana in adolescence, and to 25-50% among those who smoke marijuana daily.
• Smoke from marijuana combustion has been shown to contain a number of carcinogens and cocarcinogens, as well as many of the toxins, irritants, and carcinogens as tobacco smoke. 
• Marijuana-infused edibles account for 45% of the legal marijuana marketplace.
• AMA Marijuana has a high potential for abuse. It has no scientifically proven, currently accepted medical use for preventing or treating any disease process in the United States.

Number Using Opioids and Marijuana on the Rise

Chart: Colorado among states with growing heroin, prescription drug abuse problem 

Consistent with the past, in 2014 still only 47 percent of operators involved in traffic deaths were tested for drug impairment.

09/18/2015

The commonly heard expression that “no one ever died from a marijuana overdose” minimizes the cost of unmet potential and inability to fully engage in the challenges of daily life. Scientific research cites multiple impacts of the recreational misuse of marijuana.

09/15/2015

"We found support for the synergistic effect on an individual level; people who tend to use more marijuana also tend to use more opioids," said Scott Novak, PhD, senior research scientist at RTI International, a leading research institute in Research Triangle Park, North Carolina.
What's worrisome is that the positive association between cannabis and opioid use is growing stronger. The study found that over time, people were using these drugs more often; there were more opioids days and more cannabis days.

09/15/2015

Positive top-line results have been reported from an exploratory phase 2a placebo-controlled clinical trial of cannabidiol (CBD, GW Pharmaceuticals) in patients with schizophrenia who had failed to respond adequately to first-line antipsychotic medications.  DOES NOT CONTAIN THC.

09/14/2015

09/12/2015

This week, the Department of Health and Human Services found that marijuana use among all Americans 12 and over – especially those over 26 – significantly increased in 2014 compared to 2013. The number of 16 and 17 year-olds using marijuana in the past month also increased, (14.2% versus 15.0%).

09/09/2015

About 27% of high school students who have used both marijuana and e-cigarettes reported using the devices to vaporize cannabis. Those most likely to vaporize pot with e-cigarettes included males and younger students.

09/09/2015

There are difficulties in researching the effects of cannabis.

1. Many people who smoke cannabis also smoke tobacco. And users of cannabis often mix it with tobacco. This can make it difficult to know whether it is the tobacco, the cannabis, or both that has caused a cancer.
2. The amount of THC in cannabis also varies. Some of the cannabis available today is much stronger than it was 20 years ago. These versions contain more THC.
3. Another difficulty researchers have is in recruiting people who smoke cannabis into studies. Because cannabis is an illegal drug in many countries, people may be reluctant to take part in research. And if they do agree to take part, they may not say how much cannabis they actually smoke.

09/02/2015

09/02/2015

09/01/2015

In summary, marijuana use is harmful to children and adolescents.  For this reason, the American College of Pediatricians opposes its legalization for recreational use and urges extreme caution in legalizing it for medicinal use.  Likewise, the American Academy of Child and Adolescent Psychiatry (AACAP) recently offered their own policy statement opposing efforts to legalize marijuana. They similarly pointed out that “marijuana’s deleterious effects on adolescent brain development, cognition, and social functioning may have immediate and long-term implications, including increased risk of motor vehicle accidents, sexual victimization, academic failure, lasting decline in intelligence measures, psychopathology, addiction, and psychosocial and occupational impairment.” 

09/01/2015

"There is some more welcome news for parents as they send their children off to college this fall. Perhaps the most important is that 5 out of every 10 college students have not used any illicit drug in the past year, and more than three-quarters have not used any in the prior month."
Alongside regular users, the number of occasional marijuana users has also increased. Between 2006 and 2014, the percentage of students who reported using marijuana once or more in the prior 30 days increased from 17% to 21%. During the same period, the percentage reporting use in the past year increased from 30% to 34%.

08/31/2015

Does this sound like someone concerned about sick people?  What is he really compassionate about?  

08/28/2015

Moreover, in the men in the study who smoked marijuana and used other recreational drugs, the sperm counts were reduced by 55 percent, and the sperm concentrations were reduced by 52 percent, compared with men who hadn't used the drugs.

08/25/2015

08/21/2015

Data released Tuesday indicate that the number of Washington drivers involved in deadly crashes who tested positive for active marijuana doubled from 2013 to 2014 - the first year of legal marijuana sales in the state.

08/19/2015

Overall, these studies seem to indicate that cannabinoids have a significant role to play in the management of chronic pain. However, there are important issues that limit the validity of this conclusion. First and most important is how the improvement in pain was evaluated. In many of the studies, only instruments to measure the level of pain, most notably the Visual Analogue Scale, were used. This is fine when one is measuring acute pain. But when it comes to chronic pain—which is what the studies were looking at—the most important measures of the impact of any treatment are improvement in functioning and other objective measures, such as reduction in use of analgesic medications.
he review found minimal evidence that cannabinoids are beneficial for the nausea and vomiting associated with chemotherapy or for stimulation of appetite in patients with HIV/AIDS. It also found no evidence of effectiveness for the treatment of glaucoma or mental disorders; instead, it found that cannabinoids were more likely to worsen the latter. There was some evidence that cannabinoids might be beneficial for the spasticity associated with multiple sclerosis, but even here the results did not reach statistical significance. 
Current research has fallen far short of criteria required by the FDA to approve any drug, much less for conditions not considered acutely life-threatening and for which there are already many other effective and safe treatments. The variation from state to state as to which medical conditions are approved for cannabinoid use is not because lawmakers have ignored scientific evidence. Rather, it reflects the absence of such evidence and an approval process based on politics, not science.

08/15/2015

08/15/2015

Pharmacokinetics encompasses the absorption of cannabinoids following diverse routes of administration and from different drug formulations, the distribution of analytes throughout the body, the metabolism of cannabinoids by different tissues and organs, the elimination of cannabinoids from the body in the feces, urine, sweaty oral fluid, and hair, and how these processes change over time. Cannabinoid pharmacokinetic research has been especially challenging because of low analyte concentrations, rapid and extensive metabolism, and physio-chemicaI characteristics that hinder the separation of drugs of interest from biological matrices and from each other, and that lower drug recovery because of adsorption of compounds of interest to multiple surfaces. Mass spectrometric developments now permit highly sensitive and specific measurement of cannabinoids in a wide variety of biological matrices.

08/13/2015

THC is a large, fat-soluble molecule whose concentration in the blood rapidly drops as it is sequestered into the body’s fat stores, including the brain.  Immediately after smoking a joint, the THC level will be very high in the blood and very low in the brain.  The THC level in the brain climbs rapidly at the same time that as it is declining in the blood.  At some point, the concentrations cross, and the concentration continues to rise in the brain while it is still declining in the blood, since the brain acts like a sponge, soaking up the partially insoluble THC from the blood.  

08/09/2015

People who drive within three hours of smoking marijuana are at nearly twice the risk of being in an accident that leads to serious injury or death, compared with sober drivers, according to a new review of the research.
While driving stoned is clearly risky — and combining marijuana with alcohol is even more dangerous — drunk driving remains a bigger hazard on the road. Driving with a blood alcohol concentration of .08 — the legal limit — nearly triples the risk of crashing; a blood alcohol concentration of .10 almost quintuples it. Although drunk driving deaths have dropped by more than half since 1982, they still represent about one-third of all auto fatalities and kill about 11,000 people annually.

08/03/2015

Here is why there is confusion: the only time someone is sentenced to jail for smoking pot is if there is a more serious crime they are clearly guilty of, and the prosecutor or judge wants to give them a lighter sentence. Theft or burglary were the most common crimes I came across. Instead of being required to sentence a defendant to a year imprisonment for stealing, a defendant could plead guilty to marijuana possession instead and get a much lesser sentence. So on paper, it looks like they are serving time for drug possession, but in reality, they were let off the hook for a serious crime.

08/02/2015

07/31/2015

07/29/2015

Mr. Wright was confident that a new anticancer drug called Krebiozen would cure him. Mr. Wright’s tumors had shrunk by half, and after 10 more days of treatment he was discharged from the hospital. And yet the other patients in the hospital who had received Krebiozen showed no improvement.

07/27/2015

Current marijuana use was positively related to frequency of child physical abuse and negatively related to physical neglect.Density of medical marijuana dispensaries and delivery services was positively related to frequency of physical abuse. As marijuana use becomes more prevalent, those who work with families, including child welfare workers must screen for how marijuana use may affect a parent's ability to provide for care for their children, particularly related to physical abuse.

07/27/2015

Trends in cannabis use suggest that twice as many males as females use the drug. This gender ratio is mirrored in rates of psychosis with males outnumbering females by 2:1. However, researchers at the University of York found there is a significant widening of this ratio for cannabis psychosis, where males outnumber females by four to one.

07/24/2015

07/21/2015

07/16/2015

Safety concerns coupled with a lack of evidence of efficacy in controlled studies result in a risk/benefit ratio that does not support use of marijuana for treatment of seizures at this time. Healthcare professionals, patients, and caregivers are reminded that use of marijuana for epilepsy may not be advisable due to this lack of information on safety and efficacy. 

07/16/2015

“Telling someone to use marijuana for PTSD or any mental health problem is like telling them to go get drunk,” says one specialist who has treated the disorder among veterans and active-duty service members for more than 15 years.

07/15/2015

Smoke is harmful to lung health. Whether from burning wood, tobacco or marijuana, toxins and carcinogens are released from the combustion of materials. Smoke from marijuana combustion has been shown to contain many of the same toxins, irritants and carcinogens as tobacco smoke.4-7

07/14/2015

Adolescent marijuana use, particularly consistent use throughout adolescence, is associated with perpetration or both perpetration of and victimization by intimate partner violence in early adulthood. These findings have implications for intimate partner violence prevention efforts, as marijuana use should be considered as a target of early intimate partner violence intervention and treatment programming.

07/13/2015

For every military veteran appearing in a Colorado public meeting to advocate for the right to use marijuana to treat post-traumatic stress disorder, mental health professionals throughout Colorado estimate they’ve worked with thousands whose pot use made their PTSD — and their lives in general — much worse.
“I have seen marijuana use create so many more problems than it solves,” said Brian Lanier, a licensed clinical social worker and Army reservist in Colorado Springs who has worked more than 15 years with veterans and active-duty service members. “If nothing else, these people are just numbing themselves, which is definitely not appropriate treatment for PTSD. Telling someone to use marijuana for PTSD or any mental health problem is like telling them to go get drunk.”

07/12/2015

A separate analysis of edible marijuana found that many products laced with pot, such as drinks, baked goods and candy, misrepresent the potency of THC, the active ingredient on the labels. Only 13 of 75 products tested were accurately labeled, making reads of their potency and its effects little more than a guessing game.
Celebrating the medical benefits, if any, of marijuana has been an effective ruse to win social acceptance for getting high. This was thoroughly predictable, and now it’s clear that the organized pot heads have been blowing smoke at us.

07/11/2015

Heroin use is part of a larger substance abuse problem.

Nearly all people who used heroin also used at least 1 other drug. Most used at least 3 other drugs.
Heroin is a highly addictive opioid drug with a high risk of overdose and death for users.
People who are addicted to…

Alcohol are 2 times more likely to become addicted to heroin.
Marijuana are 3 times more likely to become addicted to heroin.
Cocaine are 15 times more likely to become addicted to heroin..
Prescription opioid painkillers are 40 times more likely to become addicted to heroin.
SOURCE: National Survey on Drug Use and Health (NSDUH), 2011-2013.

07/11/2015

PLEASE note:  23 states in the US have legalized marijuana- using the entire plant as medicine not isolating specific cannabinoids as done in research labs.
However, Dr. McCormick was quick to warn of the dangers of individuals self-medicating, but stated he hopes the research would lead to a "safe synthetic equivalent being available in the future."

07/10/2015

The principal psychoactive constituent of cannabis is Δ9-tetrahydrocannabinol (THC). THC administered intravenously is characterized by the appearance of psychopharmocological effects within 5 minutes, which continue for at least 90 minutes, providing an excellent experimental window.[12] In within-subjects tests with nonclinical volunteers, D'Souza, in particular, has shown that intravenous administration of THC causes schizophrenia-like symptoms, perceptual disturbances, anxiety, and impaired working memory (eg, Morrison et al[13] and D'Souza et al[14,15]). Similar but more pronounced results were found in patients with schizophrenia.[15]

07/08/2015

However, there is little science about the safety or efficacy of treating children with medical marijuana. Research also indicates that the brains and nervous systems of children and adolescents are especially vulnerable to adverse effects of marijuana use, a concern raised by the American Academy of Pediatrics and American Academy of Child and Adolescent Psychiatry.  Poll

07/07/2015

Ellen Snelling, chairman of the Anti-Drug Alliance, lives in Temple Terrace and often participates in the parade. She said the float and the NORML organizers who accompanied it and handed out fliers were out of place at a family-friendly event.
“When you promote drug legalization on a float in a parade, it can give a really bad message to children,” Snelling said. “I believe in free speech, but I think there is a time and a place to conduct speech referring to legalization of drugs, and a children’s parade is not that place.”
Snelling also questioned if the members of the Central Florida NORML chapter used deception to get the float in the parade. She said when she first saw the float it was an unadorned boat, but when she came back 20 minutes later, the wagon was festooned with NORML banners. Atop the green and white float was a fake 10-foot marijuana cigarette, painted red on the tip as if burning.

07/06/2015

Seeing advertisements for medical marijuana was related to middle school adolescents' intentions to use marijuana and their actual marijuana use one year later. Researchers say this is particularly important given that the mean age of adolescents surveyed was 13 and initiation of marijuana use during early adolescence is associated with poor school performance, neuropsychological performance deficits and further use of other illicit drugs, such as heroin and cocaine.

07/06/2015

Adolescents who saw advertising for medical marijuana were more likely to either report using marijuana or say they planned to use the substance in the future, according to a new RAND Corporation study.